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    Legal Status

    California

    Mixed

    Last updated September 15, 2025

    This is informational only and does not constitute legal advice. Laws change frequently. Consult qualified legal counsel in California for specific guidance.

    Substance-by-Substance Status

    KetamineLegal
    PsilocybinDecriminalized
    MDMATrials Only
    AyahuascaIllegal
    IbogaineIllegal

    Policies & Regulations

    Decriminalization

    Proposed

    Multiple California cities (Oakland, Santa Cruz, San Francisco) have deprioritized enforcement of laws against natural psychedelics. A statewide decriminalization bill (SB 58) was vetoed by the governor in 2023 but revised legislation is expected in 2025-2026. Ketamine therapy is available through standard medical channels.

    What's Allowed

    • •Ketamine therapy via licensed clinics (standard medical use)
    • •MDMA therapy through FDA clinical trials
    • •Local deprioritization of natural psychedelics in Oakland, Santa Cruz, SF

    Not Allowed

    • •Psilocybin service centers (no state framework yet)
    • •Commercial sale or distribution of psychedelics
    • •Ayahuasca or ibogaine administration

    How to Access

    1. 1.Seek ketamine therapy through licensed medical providers
    2. 2.Search ClinicalTrials.gov for MDMA or psilocybin trials in California
    3. 3.In Oakland/Santa Cruz/SF, personal use of natural psychedelics is lowest law enforcement priority

    Official Resources

    California SB 58 (2023 — Vetoed)Oakland Resolution on Natural Psychedelics

    Last updated: September 15, 2025

    Recent Changes

    September 15, 2025

    New psilocybin decriminalization bill introduced in California legislature. Bill includes regulated therapeutic access framework.

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